Prokaryotic Replication

This section covers chromosome replication in E. coli which involves bidirectional replication from a single origin. Bidirectional refers to that fact that replication proceeds in both directions from the origin. In each direction a growing fork moves along the chromosome; each fork involves the separation of the double stranded helix so that the two separated strands can each be used as a template for the synthesis of a new stand. The first page (General features) covers some elements that are common to all DNA replication systems. The other three cover aspects that are specific to E. coli

For this section you should understand:

• General features of replication


• Initiation


• Elongation


• Termination